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GABA RECEPTORS
Descriptors Found:
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DeCS
Descriptor
English
:
Receptors, GABA
Descriptor
Spanish
:
Receptores de GABA
Descriptor
Portuguese
:
Receptores de GABA
Synonyms
English
:
gamma-Aminobutyric Acid Receptors
GABA Receptors
Receptors, gamma-Aminobutyric Acid
Tree Number:
D12.776.543.750.720.200.300
Definition
English
:
Cell-surface
proteins
that bind
GAMMA-AMINOBUTYRIC ACID
with high affinity and trigger changes that influence the
behavior
of cells. GABA-A receptors
control
chloride channels
formed by the receptor complex itself. They are blocked by
bicuculline
and usually have modulatory sites sensitive to
benzodiazepines
and
barbiturates
. GABA-B receptors act through G-proteins on several effector systems, are insensitive to
bicuculline
, and have a high affinity for L-baclofen.
Indexing Annotation
English
:
GEN; prefer specifics; DF: RECEPT GABA
Entry Combination - descr/qualif
English
:
Receptors, GABA
/
agonists
use
GABA Agonists
Receptors, GABA
/
antagonists & inhibitors
use
GABA Antagonists
See Related
English
:
GABA Plasma Membrane Transport Proteins
History Note
English
:
94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93
Allowable Qualifiers
English
:
AD
administration & dosage
AN
analysis
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
31127
Unique Identifier:
D018079
Occurrence in VHL
:
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